HEPTALDEHYDE SODIUM BISULFITE Application : In antifungal compositions. 1. Heptaldehyde compounds such as heptaldehyde and heptaldehyde bisulfite are exceptionally effective in inhibiting the growth of, or killing pathogenic fungus infection of the skin and particularly, the fungi of the genus Trichophyton which are responsible for tinea pedis. 2. Heptaldehyde bisulfite is an effective fungicidal and fungistatic agent against the dermatophytes responsible for common rnycotic infection even at lower concentrations.Heptaldehyde is also effective against all the listed dermatophytes at 0.5% concentration. 3. Heptaldehyde sodium bisulfite is nontoxic to humans and lower animals and non-irritating to the skin 4. Heptaldehyde and heptaldehyde bisulfite are effective over a wide range of pH. 5. Heptaldehyde and heptaldehyde bisulfite can be incorporated into the standard types of ointment bases. 6. Heptaldehyde and Heptaldehyde bisulfite may also be used in the form of a dermatologic dusting powder by combining them with a diluent powder consisting substantially of talc, fullers earth or other inert natural diluent powders. 7. Heptaldehyde bisulfite can also be used as a dusting powder in its undiluted state. 8. Heptaldehyde bisulfite can be incorporated into a 70% aqueous ethyl alcoholsolution to the extent of 5% 9. Heptaldehyde bisulfite is non-volatile and therefore, is retained longer on the surfaces where it is applied.
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